Performance evaluation of serum low density lipoprotein cholesterol on automatic biochemical analyzer

Objective To evaluate the performance feature of serum low density lipoprotein cholesterol(LDL-C) on automatic biochemical analyzer.Method Referring to the evaluation protocols documents and reports,and by combining our actual work,the precision,accuracy,analytical measurement range,and biotic interval of LDL-C were verificated.Results The within-run and day precision between precision were all consistent with the claim of manufacturer.The biases of mean and target value that detected in five quality control specimens were in the range of permission.Analytical measurement range was 0~5.21 mmol/L,that wider than the manufacture′s claim slightly.The biological reference range validated the given was used in their lab.Different concentrations of free bilirubin,direct bilirubin,chylomicrons,hemoglobin will not influence LDL-C detection.Conclusion The main analytical performances of serum total bile acid on automatic biochemical analyzer were consistent with the claim defined by manufacturer,and could be satisfied with the clinical determination.