Investigation and analysis of use of antibiotics during perioperative period of type I surgery

OBJECTIVE To investigate the use of antibiotics during perioperative period of type Ⅰ incision surgery so as to provide basis for the reasonable use and standard management of antibiotics.METHODS The clinical data of 135 patients who underwent the type Ⅰ surgery and discharged from Aug to Oct 2011 were investigated retrospectively.The use of antibiotics,drug delivery timing,time of prophylactic antibiotics,choice of antibiotics,and combination use of antibiotics were comprehensively analyzed.RESULTS All the 135 patients used antibiotics during the perioperative period with the utilization rate of 100.0%,there were 87(64.44%) patients who were given antibiotics 0.5 h-2 h before the surgery,12(8.89%) patients more than 2 hours before the surgery,3(2.22%) patients receivingintraoperatively,33(2.65%) receiving postoperatively,35(37.14%) patients with operation duration more than 3 hours,and 13(37.14%) patients receiving additional second dose of antibacterial drugs.There were 35(25.92%) patients with the total prophylactic duration less than 24 hours,20(14.81%) patients with the duration between 25 hours and 48 hours,and 80(59.27%) patients with the duration more than 48 hours.The patients who chose the first generation of cephalosporin only accounted for 21.48%,there were 93(68.89%) patients who used the single drug,and 42(31.11%) using two-drug,there was no cases using three-drug or four-drug.CONCLUSION There has been problems existing during the perioperatvie period such as the inappropriate drug delivery time,extended duration of postoperative medication,and irrational selection of antibiotics.It is necessary to strengthen the clinical application management and promote the reasonable use of antibiotics during the perioperative period.