Application of small allogeneic bone transplantation to bone defect after excision of bone tumor

Objective To investigate the efficacy of the small cryopreserved allogenic bone transplantation in the reconstruction of bone defect caused by bone tumor.Method From November 2000 to November of 2004,the small cryopreserved allogeneic bone transplantation was successfully used in 22 patients with bone defect resulting from the tumorectomy of four limbs.Results Follow-up ranged from 6 to 80 months with an average of 30 months.One patient suffered recurrence and underwent re-resection and re-transplantation.Fractures of allograft bone appeared in three cases because of the failure of fixation and were treated with the second internal fixation.Porosis demonstrated by radiograms appeared in the other cases,and no infection appeared.Conclusions The small cryopreserved allogeneic bone transplantation is a good choice for repairing bone defect caused by the resection of benign bone tumor.It is essential to resect the tumor thoroughly,choose small cryopreserved allograft bones correctly,and use appropriate dosage of antibiotics.In addition,adequate fixation,operation skill and avoiding early weight bearing are important for the success of operation.