Efficacy observation of 18 neonates with pneumothorax treated by high frequency oscillatory ventilation

Objective To evaluate the therapeutic effect of high frequency oscillatory ventilation (HFOV) combined with thoracic cavity occlusive drainage on neonatal pneumothorax.Methods 18 neonates with pneumothoax were treated by HFOV combined with thoracic cavity occlusive drainage.The clinical efficacy was observed and blood gas parameters were detected before and after treatment.Results 12 hours after treatment,the PaCO 2 decreased from (10.10±3.20) kPa to (5.70±10.80) kPa (P0.05),the PaO 2 increased from (5.60±1.10) kPa to (7.20±1.60) kPa (P0.05).24 hours after treatment,PaO 2 was (9.30±2.00) kPa (P0.01),and FiO 2,oxygenation index and mean airway pressure decreased gradually.18 neonates were treated by HFOV and thoracic cavity occlusive drainage.14 cases were cured completely.3 cases gave up treatment and one case of bilateral pneumothorax had no effect.Conclusion HFOV is safe and quite effective in treating neonatal pneumothorax with acute respiratory failure, which is superior to conventional mechanical ventilation (CMV).