Distribution and Drug Resistance of 294 Bacteria Isolates from 4 823 Blood Culture Samples

Objective To investigate the distribution and drug resistance of bacteria isolated from blood cultures in2013,and to provide a reasonable antimicrobial therapy.Methods Blood samples were cultured with BACT/ALERT3 Dautomated blood culture system,and bacterial confirmation and antibiotic susceptibility tests were carried out with VITEK 2Compact bacterial identification system.Results A total of 294 strains of pathogenic bacteria were isolated from 4 823 blood cultures,including 176(59.8%)strains of gram positive cocci,98(33.4%)strains of gram negative bacilli and 4(1.3%)strains of fungi.The leading pathogens were Saphylococcus epidermidis,E.coli,S.hominis,S.haemolyticus,and K.pneumoniae,accounting for 25.2%,22.9%,17.3%,9.5%,and 4.9%,respectively.Staphylococcus spp.was sensitive to vancomycin,tigecycline,and rifampicin,whereas E.coli and K.pneumoniae were sensitive to imipenem,piperacillin and tazobactam.Conclusion A high rate of drug resistant bacteria strains,with various species of pathogens,was seen.The surveillance of distribution and drug resistance of bacteria should be strengthened so as to improve the clinical reasonable antibiotic therapy.