2015•China Medical HeraldRequires access

Effect of integrative Chinese and western medicine on acute exacerbation of chronic obstructive pulmonary disease combined with respiratory failure

Ke Ton

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Abstract

Objective To investigate the clinical curative effect of integrative Chinese and western medicine on chronic obstructive pulmonary disease combined with respiratory failure(AECOPD). Methods 90 patients with acute exacerbation of chronic obstructive pulmonary disease with respiratory failure admitted to the People's Hospital of Longhua New District in Shenzhen City from January 2012 to January 2014 were randomly divided into two groups, with 45 cases in each group, the control group was treated with conventional western treatment, the observation group was treated with TCM Qingfei Huatan Decoction orally based on the treatment of control group. The main symptoms of cough, expectoration, gasp and wheeze integral and partial pressure of oxygen(PaO2), carbon dioxide partial pressure(PaCO2), white blood cell count(WBC), serum D- two dimers(D-D) changes before and after treatment in the two groups were compared, and the clinical efficiency of the two groups was compared. Results There were no significant differences in the main symptoms of cough, sputum, wheezing, wheezing integral before treatment(P 0.05), the symptom integrals mentioned above after treatment of the two groups were significantly decreased(P 0.05), the observation group was lower than that of the control group, the difference was statistically significant(P 0.01); there were no significant differences in PaO2, PaCO2, WBC and D-D before treatment(P 0.05), the index mentioned above of two groups were significantly improved after treatment(P 0.05), the observation group was better than the control group, the difference was statistically significant(P 0.01), the total effective rate of the observation group was higher than that of the control group, the difference was statistically significant(P 0.05). Conclusion Integrative Chinese and western medicine on acute exacerbation of chronic obstructive pulmonary disease combined with respiratory failure can effectively alleviate the symptoms, improve the blood gas index analysis, improve the clinical efficacy, it has good safety and clinical application value.

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What this paper is about

Objective To investigate the clinical curative effect of integrative Chinese and western medicine on chronic obstructive pulmonary disease combined with respiratory failure(AECOPD). Methods 90 patients with acute exacerbation of chronic obstructive pulmonary disease with respiratory failure admitted to the People's Hospital of Longhua New District in Shenzhen City from January 2012 to January 2014 were randomly divided into two groups, with 45 cases in each group, the control group was treated with conventional western treatment, the observation group was treated with TCM Qingfei Huatan Decoction orally based on the treatment of control group. The main symptoms of cough, expectoration, gasp and wheeze integral and partial pressure of oxygen(PaO2), carbon dioxide partial pressure(PaCO2), white blood cell count(WBC), serum D- two dimers(D-D) changes before and after treatment in the two groups were compared, and the clinical efficiency of the two groups was compared. Results There were no significant differences in the main symptoms of cough, sputum, wheezing, wheezing integral before treatment(P 0.05), the symptom integrals mentioned above after treatment of the two groups were significantly decreased(P 0.05), the observation group was lower than that of the control group, the difference was statistically significant(P 0.01); there were no significant differences in PaO2, PaCO2, WBC and D-D before treatment(P 0.05), the index mentioned above of two groups were significantly improved after treatment(P 0.05), the observation group was better than the control group, the difference was statistically significant(P 0.01), the total effective rate of the observation group was higher than that of the control group, the difference was statistically significant(P 0.05). Conclusion Integrative Chinese and western medicine on acute exacerbation of chronic obstructive pulmonary disease combined with respiratory failure can effectively alleviate the symptoms, improve the blood gas index analysis, improve the clinical efficacy, it has good safety and clinical application value.

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Available abstract

Objective To investigate the clinical curative effect of integrative Chinese and western medicine on chronic obstructive pulmonary disease combined with respiratory failure(AECOPD). Methods 90 patients with acute exacerbation of chronic obstructive pulmonary disease with respiratory failure admitted to the People's Hospital of Longhua New District in Shenzhen City from January 2012 to January 2014 were randomly divided into two groups, with 45 cases in each group, the control group was treated with conventional western treatment, the observation group was treated with TCM Qingfei Huatan Decoction orally based on the treatment of control group. The main symptoms of cough, expectoration, gasp and wheeze integral and partial pressure of oxygen(PaO2), carbon dioxide partial pressure(PaCO2), white blood cell count(WBC), serum D- two dimers(D-D) changes before and after treatment in the two groups were compared, and the clinical efficiency of the two groups was compared. Results There were no significant differences in the main symptoms of cough, sputum, wheezing, wheezing integral before treatment(P 0.05), the symptom integrals mentioned above after treatment of the two groups were significantly decreased(P 0.05), the observation group was lower than that of the control group, the difference was statistically significant(P 0.01); there were no significant differences in PaO2, PaCO2, WBC and D-D before treatment(P 0.05), the index mentioned above of two groups were significantly improved after treatment(P 0.05), the observation group was better than the control group, the difference was statistically significant(P 0.01), the total effective rate of the observation group was higher than that of the control group, the difference was statistically significant(P 0.05). Conclusion Integrative Chinese and western medicine on acute exacerbation of chronic obstructive pulmonary disease combined with respiratory failure can effectively alleviate the symptoms, improve the blood gas index analysis, improve the clinical efficacy, it has good safety and clinical application value.

Key concepts: Medicine, Exacerbation, Sputum, Internal medicine, Decoction, Acute exacerbation of chronic obstructive pulmonary disease, Wheeze, Pulmonary disease

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