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Relationship between Antithrombin-III and Acute Coronary Syndrome

YU Bocheng

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Abstract

Objective: To explore the relationship between antithrombin III and acute coronary syndrome(ACS).Methods: Fifty-two consecutive patients with ACS were enrolled in the study,42 cases were acute myocardial infarction(AMI),and 11 cases were unstable angina(UA),and 60 healthy subjects were chosen as controls.The plasma level of antithrombin III was measured in all subjects.Results: The levels of antithrombin III in ACS patients group was significantly lower compared to the healthy control;and the patients with AMI showed lowest levels of antithrombin III.The levels of antithrombin III increased significantly after comprehensive treatment of ACS.Conclusion: Plasma levels of antithrombin III decreased in ACS patients.The measurement of antithrombin III could be a reflection of hypercoagulation state,and it is helpful in prognosis and treatment.

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What this paper is about

Objective: To explore the relationship between antithrombin III and acute coronary syndrome(ACS).Methods: Fifty-two consecutive patients with ACS were enrolled in the study,42 cases were acute myocardial infarction(AMI),and 11 cases were unstable angina(UA),and 60 healthy subjects were chosen as controls.The plasma level of antithrombin III was measured in all subjects.Results: The levels of antithrombin III in ACS patients group was significantly lower compared to the healthy control;and the patients with AMI showed lowest levels of antithrombin III.The levels of antithrombin III increased significantly after comprehensive treatment of ACS.Conclusion: Plasma levels of antithrombin III decreased in ACS patients.The measurement of antithrombin III could be a reflection of hypercoagulation state,and it is helpful in prognosis and treatment.

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Available abstract

Objective: To explore the relationship between antithrombin III and acute coronary syndrome(ACS).Methods: Fifty-two consecutive patients with ACS were enrolled in the study,42 cases were acute myocardial infarction(AMI),and 11 cases were unstable angina(UA),and 60 healthy subjects were chosen as controls.The plasma level of antithrombin III was measured in all subjects.Results: The levels of antithrombin III in ACS patients group was significantly lower compared to the healthy control;and the patients with AMI showed lowest levels of antithrombin III.The levels of antithrombin III increased significantly after comprehensive treatment of ACS.Conclusion: Plasma levels of antithrombin III decreased in ACS patients.The measurement of antithrombin III could be a reflection of hypercoagulation state,and it is helpful in prognosis and treatment.

Key concepts: Antithrombin, Acute coronary syndrome, Unstable angina, Medicine, Internal medicine, Myocardial infarction, Cardiology, Plasma levels

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