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1985•The Journal of Japan Atherosclerosis SocietyOpen access

Clinical Significance of Urine Antithrombin III Concentration in Patients with Acute Myocardial Infarction

Tetsuji Awata, Tsutomu Yamada, Takefumi Matsuo

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Abstract

The concentration of urine antithrombin III measured by newly developed EIA method showed a marked increase in acute phase of myocardial infarction. The peak value of urinary output of AT III reached in the delay of two or three days behind the peak of heart enzymes (CPK, LDH), and had a significant correlation with the severity of clinical situation according to Killip's criteria.Therefore, it was suggested that a higher value of urinary output of AT III reflected a much more poor prognosis in acute phase of myocardial infarction.

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The concentration of urine antithrombin III measured by newly developed EIA method showed a marked increase in acute phase of myocardial infarction. The peak value of urinary output of AT III reached in the delay of two or three days behind the peak of heart enzymes (CPK, LDH), and had a significant correlation with the severity of clinical situation according to Killip's criteria.Therefore, it was suggested that a higher value of urinary output of AT III reflected a much more poor prognosis in acute phase of myocardial infarction.

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Available abstract

The concentration of urine antithrombin III measured by newly developed EIA method showed a marked increase in acute phase of myocardial infarction. The peak value of urinary output of AT III reached in the delay of two or three days behind the peak of heart enzymes (CPK, LDH), and had a significant correlation with the severity of clinical situation according to Killip's criteria.Therefore, it was suggested that a higher value of urinary output of AT III reflected a much more poor prognosis in acute phase of myocardial infarction.

Key concepts: Myocardial infarction, Antithrombin, Urine, Internal medicine, Medicine, Urinary system, Cardiology, Clinical significance

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