Effect of Foshousan on the hemorheology in rat

OBJECTIVE To observe the effect of Foshousan on the hemorheology in acute blood-stasis model rats,and the effect of platelet aggregation,platelet conglutination in healthy rats.METHODS ①Rats were divided into six groups randomly,after oral administration with Foshousan for 8 days,expect the normal control group others were soaded in ice water after being injected adrenalin hydrochloride injection,and then measured the viscosity of whole blood,erythrocyte aggregation,erythrocyte hematocrit,erythrocyte electrophoresis.②Rats were divided into six groups randomly,measured RBC,Hb,PLT,platelet aggregation,and platelet conglutination induced by ADP after oralling Foshousan ten days.RESULTS Foshousan,Angelica and Ligusticum all could reduce the viscosity of whole blood,erythrocyte aggregation,hematocrit,rigidity,deformability,electrophoresis,platelet aggregation,platelet conglutination and also it can increase RBC,Hb,PLT.But the effect of Foshousan is better than Angelica and Ligusticum.CONCLUSION Foshousan can ameliorate hemorheology and enrich blood.And the effect of Foshousan is better than Angelica and Ligusticum.