Clinical effect observation of prednisone acetate and budesonide combined with endoscopic sinus surgery on nasal polyps

Objective To observe the therapeutic effect of prednisone acetate and budesonide conbined with endoscopic sinus surgery on nasal polyps. Methods 74 cases of nasal polyps patients who were admitted into the author's hospital were divided into control group and combined treating group randomly,37 cases in each group.The control group was mono- therapied with endoscopic sinus surgery,and the combined group was treated with prednisone acetate and budesonide inaddition to surgery,the intraoperative bleeding,postoperative recurrence rate and overall response rate were selected as the indicators for clinical effect. Results The intraoperative bleeding, postoperative recurrence rate and overall response rate of combined treating group were(41.5±6.9)mL,21.4% and 88.9%,compared with(69.2±7.1)mL,32.5% and 75.9% of control group,had a significant difference(P 0.05 or P 0.01). Conclusion Glucocorticoid combined with endoscopic sinus surgery has a significant clinical effect on the nasal polyps,its effect superior to the monotherapy of endoscopic sinus surgery,and has a promoted value in clinical therapy.