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Preparation of Baicalin Liposome and Determination of its Entrapment Efficiency

Runxian Yang

Open publisher page 1 citations

Abstract

Baicalin Liposome was prepared with the phospholipids by reverse-phase evaporation method.The concentration and entrapment efficiency of Baicalin Liposome was determined by UV and dialysis method respectively The optimum conditions were: m(EPC):m(CHOL)=4:1,m(organic phase):m(aqueous phase)=3:1,concentration of Baicalin 1.5mg/mL.The size distribution was symmetrical and the amount was large and the entrapment efficiency was 40.4%.

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What this paper is about

Baicalin Liposome was prepared with the phospholipids by reverse-phase evaporation method.The concentration and entrapment efficiency of Baicalin Liposome was determined by UV and dialysis method respectively The optimum conditions were: m(EPC):m(CHOL)=4:1,m(organic phase):m(aqueous phase)=3:1,concentration of Baicalin 1.5mg/mL.The size distribution was symmetrical and the amount was large and the entrapment efficiency was 40.4%.

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Available abstract

Baicalin Liposome was prepared with the phospholipids by reverse-phase evaporation method.The concentration and entrapment efficiency of Baicalin Liposome was determined by UV and dialysis method respectively The optimum conditions were: m(EPC):m(CHOL)=4:1,m(organic phase):m(aqueous phase)=3:1,concentration of Baicalin 1.5mg/mL.The size distribution was symmetrical and the amount was large and the entrapment efficiency was 40.4%.

Key concepts: Baicalin, Entrapment, Liposome, Chemistry, Chromatography, Aqueous two-phase system, Aqueous solution, Evaporation

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