ScholarLens Back to search
2000•Qilu yixue zazhiRequires access

IMMUNOHISTOCHEMICAL STUDIES OF ANGIOGENESIS IN HUMAN PROSTATIC CANCER

Fenggang Xiang

Open publisher page 0 citations

Abstract

Objective To investigate the biological significance of tumor angiogenesis in human prostatic Methods Microvessel density (MVD) in 38 cases of invasive prostatic cancer were detected using immunohistochemical techniques (LSAB). Results The morphology of tumor microvessel was obviously various. Microvessel density in highly differentiated prostatic cancer was significantly lower than that in poorly differentiated and undifferentiated prostatic cancer, respectively( F=6.48, q=3.80, 4.86, P 0.05, 0.01). In carcinoma, with positive lymph node metastasis, microvessel density was significantly higher than that in node negative carcinoma ( t=3.76,P 0.001). Conclusion The results suggest that angiogenesis assessed by MVD plays an important role in the invasion and metastasis of human prostatic cancer. [

About this research paper

What this paper is about

Objective To investigate the biological significance of tumor angiogenesis in human prostatic Methods Microvessel density (MVD) in 38 cases of invasive prostatic cancer were detected using immunohistochemical techniques (LSAB). Results The morphology of tumor microvessel was obviously various. Microvessel density in highly differentiated prostatic cancer was significantly lower than that in poorly differentiated and undifferentiated prostatic cancer, respectively( F=6.48, q=3.80, 4.86, P 0.05, 0.01). In carcinoma, with positive lymph node metastasis, microvessel density was significantly higher than that in node negative carcinoma ( t=3.76,P 0.001). Conclusion The results suggest that angiogenesis assessed by MVD plays an important role in the invasion and metastasis of human prostatic cancer. [

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To investigate the biological significance of tumor angiogenesis in human prostatic Methods Microvessel density (MVD) in 38 cases of invasive prostatic cancer were detected using immunohistochemical techniques (LSAB). Results The morphology of tumor microvessel was obviously various. Microvessel density in highly differentiated prostatic cancer was significantly lower than that in poorly differentiated and undifferentiated prostatic cancer, respectively( F=6.48, q=3.80, 4.86, P 0.05, 0.01). In carcinoma, with positive lymph node metastasis, microvessel density was significantly higher than that in node negative carcinoma ( t=3.76,P 0.001). Conclusion The results suggest that angiogenesis assessed by MVD plays an important role in the invasion and metastasis of human prostatic cancer. [

Key concepts: Angiogenesis, Medicine, Immunohistochemistry, Microvessel, Metastasis, Cancer, Pathology, Carcinoma

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
IMMUNOHISTOCHEMICAL STUDIES OF ANGIOGENESIS IN HUMAN PROSTATIC CANCER — Research Paper | ScholarLens