Clinical application of serum high sensitivity C reactive protein detected in coronary heart disease patients

Objective It is to study and check the clinical application value of the changes of serum high sensitivity C reactive protein(hs-CRP) levels in coronary heart disease(CHD).Methods The contents of serum hs-CRP in normal control (n=50),stable angina pectoris(SAP)(n=58),unstable angina pectoris(UAP)(n=39) and acute myocardial infarction(AMI)(n=31) were quantitatively detected with latex strengthen transmission immunoturbidimetry(ITM).The relation between hs-CRP and CHD and the changes of hs-CRP content before and after treatment were analyzed.Results The concentrations of serum hs-CRP in normal control,SAP,UAP and AMI groups were respectively(0.98±0.76) mg/L,(3.12±0.71) mg/L,(5.26±1.48) mg/L and(8.83±3.75) mg/L.The concentration of serum hs-CRP raised up in turn in the four groups.There were significantly different among the four groups(P0.01).The concentrations of serum hs-CRP in SAP,UAP and AMI groups after treatment were respectively(2.56±0.60) mg/L,(3.29±0.95) mg/L and(3.98±1.32) mg/L,there were significantly different compared with that before treatment(SAP group P0.05,UAP group and AMI group P0.01).Conclusion Serum hs-CRP has important significance in predicting severity degree of cardiovascular lesion,preventing cardiovascular disease and observing curative effect.