Expression characteristic of serum high-sensitivity C-reactive protein in coronary heart disease

Objective To discuss the expression characteristic of high-sensitivity C-reactive protein(hs-CRP) in coronary heart disease.Methods 115 patients of coronary heart disease confirmed by coronary angiography were randomly recruited, including 42 cases of acute myocardial infarction(AMI),34 cases of unstable angina pectoris(UAP) and 39 cases of stable angina pectoris(SAP). Another 50 patients of healthy persons were recruited as control group. Their levels of serum hs-CRP were determined by particle enhanced immuoturbidimetric method at the analysis instrument of Olympus AU2700.Later the variation of hs-CRP before and after treating was analysed.Results hs-CRP concentration of CHD patients was significantly higher than that of the control group(P0.01).The levels of hs-CRP of AMI group were significantly higher than those in UAP group.The levels of hs-CRP of UAP group were significantly higher than those in SAP group (P0.01). There was significant difference in the levels of hs-CRP of every CHD groups before and after treatment(P0.01).Conclusion The level of serium hs-CRP in CHD is significantly higher than that of the control,which indicates that inflammation may occur in CHD.It is of great value to the diagnosis,treatment and prognosis of CHD.