2002•Journa of Henan Medical UniversityRequires access

Expression of CD44v6 in gastric cancer and its adjacent cancer tissues

Yun Zhou

Abstract

Aim: To study the relationship between the expression of CD44v6 protein and clinical pathological characterizations of gastric cancer and its adjacent cancer tissues.Methods:Immunohistochemistry S P method was used.Results:Immunoreactivity for CD44v6 was not found in normal gastric tissues; in the adjacent cancer tissues, the weak positive rate of CD44v6 was 35%, while in gastric cancer, the positive rate of CD44v6 was 64.4%;the positive rates of CD44v6 was correlated with histological types, depth of invasion, and lymph node metastasis of gastric cancer. Conclusion:These data suggest that the expression of CD44v6 protein may be useful for evaluating biological behavior of gastric cancer.

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Key concepts: Cancer, Immunohistochemistry, Pathological, Medicine, Cancer cell, Lymph node metastasis, Metastasis, Pathology