Study on the Extractive Technology of Chlorogenic Acid from the Leaves of Eucommia ulmoides

Main factors influencing the extraction of chlerogenic acid from the leaves of Eucommia ulmoides were studied by single factor experiments, and then the response surface analysis was used to optimize conditions for the extraction of chlorogenle acid. Optimized conditions for the extraction of chlorogenle acid was obtained as: ethanol concentration 52%; extraction temperature 78℃; material to solvent 1:13, extraction time 2h, and extraction for twice. The extraction ratio of chlorogenic acid and the yield of extract were 2.38%, 18.38%, respectively, and the purity of chlorogenic acid was 12.97% in the optimized conditions.