2009•Journal of Yunnan University of Traditional Chinese MedicineRequires access

Protective Effect of DYJHGF on Acute Liver Injury Induced by CCl_4 in Mice

Chao Zhang

Abstract

Objective:To study the protective effect of DYJHGF on acute liver injury induced by CCl4 in mice.Methods: DYJHGF was administered by pouring it into stomachs of mice for seven days preventatively,and then,acute liver injury model was induced by CCl4.ALT and AST activities were measured.ResuLts:Different concentrations of the DYJHGF significantly decreased the activities of serum ALT and AST(P0.05),and lighten the extent of degeneration and necrosis.Conclusion: DYJHGF showed protective effects on acute liver injury induced by CCl4 in mice significantly.

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Key concepts: CCL4, Liver injury, Medicine, Acute injury, Necrosis, Liver tissue, Histopathological examination, Liver damage