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[Preparation of Zhongjiefeng dispersible tablets].

Zhenfeng Wu, Wei He, Yong Li

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Abstract

OBJECTIVE: To prepare Zhongjiefeng dispersible tablets. METHODS: The formulation of Zhongjiefeng dispersible tablets were optimized as index of disintegration time by orthogonal design test. RESULTS: The optimized Zhongjiefeng dispersible tablets, which were prepared by selecting 16% PVPP and 3% L-HPC as disintegrants, 40% MCC as filler, can disintegrate in 3 mins. CONCLUSIONS: The above formulation is reasonable and the disintegration time is suitable, so it can provide theoretic support for industrialization.

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What this paper is about

OBJECTIVE: To prepare Zhongjiefeng dispersible tablets. METHODS: The formulation of Zhongjiefeng dispersible tablets were optimized as index of disintegration time by orthogonal design test. RESULTS: The optimized Zhongjiefeng dispersible tablets, which were prepared by selecting 16% PVPP and 3% L-HPC as disintegrants, 40% MCC as filler, can disintegrate in 3 mins. CONCLUSIONS: The above formulation is reasonable and the disintegration time is suitable, so it can provide theoretic support for industrialization.

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Available abstract

OBJECTIVE: To prepare Zhongjiefeng dispersible tablets. METHODS: The formulation of Zhongjiefeng dispersible tablets were optimized as index of disintegration time by orthogonal design test. RESULTS: The optimized Zhongjiefeng dispersible tablets, which were prepared by selecting 16% PVPP and 3% L-HPC as disintegrants, 40% MCC as filler, can disintegrate in 3 mins. CONCLUSIONS: The above formulation is reasonable and the disintegration time is suitable, so it can provide theoretic support for industrialization.

Key concepts: Materials science, Chromatography, Filler (materials), Chemical engineering, Chemistry, Composite material, Engineering

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