STUDY ON SCREENING OF FORMULA OF HYDROGEN PEROXIDE FOAM DISINFECTANT
Zhu Da-lan, Zhang Wen-fu
Abstract
Zhu Da-lan, Zhang Wen-fu
Abstract
Modified Warring Blender test and disinfectant screening test were used to study the foam emulsifier and foam stabilizer of foamtype hydrogen peroxide disinfectant.Results: The disinfectant containing dodecyl dimethyl benzyl ammonium chloride 48 g/L produced most abundant foam(P0.05) and that containing arabic gum 3 g/L was most stable and its half life attained 31 min(P0.05).Orthogonal design was used to optimize the formula and following results were obtained by statistical treatment: the hydrogen peroxide foam disinfectant containing 50.7 g/L hydrogen peroxide,48 g/L dodecyl dimethyl benzyl ammonium chloride and 3 g/L arabic gum as the main ingredients with a 60 min contact time killed 99.94% of spores of Bacillus subtilis var.niger in suspension.After the disinfectant was stored at 54℃ for 14 d,its hydrogen peroxide content decreased by 3.35%.Conclusion: The disinfectant containing hydrogen peroxide,dodecyl dimethyl benzyl ammonium chloride and arabic gum has good foam-forming efficacy with high germicidal ability and is stable.
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Modified Warring Blender test and disinfectant screening test were used to study the foam emulsifier and foam stabilizer of foamtype hydrogen peroxide disinfectant.Results: The disinfectant containing dodecyl dimethyl benzyl ammonium chloride 48 g/L produced most abundant foam(P0.05) and that containing arabic gum 3 g/L was most stable and its half life attained 31 min(P0.05).Orthogonal design was used to optimize the formula and following results were obtained by statistical treatment: the hydrogen peroxide foam disinfectant containing 50.7 g/L hydrogen peroxide,48 g/L dodecyl dimethyl benzyl ammonium chloride and 3 g/L arabic gum as the main ingredients with a 60 min contact time killed 99.94% of spores of Bacillus subtilis var.niger in suspension.After the disinfectant was stored at 54℃ for 14 d,its hydrogen peroxide content decreased by 3.35%.Conclusion: The disinfectant containing hydrogen peroxide,dodecyl dimethyl benzyl ammonium chloride and arabic gum has good foam-forming efficacy with high germicidal ability and is stable.
Key concepts: Disinfectant, Hydrogen peroxide, Chemistry, Ammonium chloride, Nuclear chemistry, Polyvinyl chloride, Gum arabic, Peroxide