2006•Chinese Journal of DisinfectionRequires access

STUDY ON GERMICIDAL REGULARITY OF HYDROGEN PEROXIDE FOAM DISINFECTANT

Zhang Wen-fu

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Abstract

In order to observe the germicidal regularity of hydrogen peroxide foam disinfectant,carrier immersion quantitative germicidal test was used to carry out systematic study in laboratory.Results:The average killing rates of Bacillus subtilis var.niger spores on cloth strip exposed to the stock solution of the foam disinfectant containing hydrogen peroxide 45 g/L for 60 min and spores of vaccine strain of Bacillus anthracis exposed for 30 min were higher than 99.9%.The natural logarithm of survival rate of different bacterial spores showed linear regression with exposure time to hydrogen peroxide foam disinfectant.In the range of 10℃~40℃,the efficacy of hydrogen peroxide foam disinfectant in killing B.subtilis var.niger spores was enhanced with increasing temperature.The adjuvant in hydrogen peroxide foam disinfectant formula had synergetic effect on germicidal efficacy and the synergetic efficacy coefficient in killing B.subtilis var.niger spores was 4.13.The average killing rates of Candida albicans on cloth strip exposed to the foam disinfectant solution containing hydrogen peroxide 15 g/L for 1 min,Staphylococcus aureus on cloth strip exposed to the foam disinfectant solution containing hydoogen peroxide 4.5 g/L for 5 min and Escherichia coli on cloth strip exposed to the foam disinfectant solution containing hydrogen peroxide 2.25 g/L for 1 min were 99.9%.The nutrient broth as organic substance had significant influence on efficacy of the hydrogen peroxide foam disinfectant in killing F_2 coliphage.Change of organic interfering substance content had no significant influence on efficacy of the hydrogen peroxide foam disinfectant in killing B.subtilis var.niger spores.Conclusion: The germicidal regnlarity of the hydrogen peroxide foam disinfectant essentially conforms to the germicidal regularity of common chemical disinfectant.

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In order to observe the germicidal regularity of hydrogen peroxide foam disinfectant,carrier immersion quantitative germicidal test was used to carry out systematic study in laboratory.Results:The average killing rates of Bacillus subtilis var.niger spores on cloth strip exposed to the stock solution of the foam disinfectant containing hydrogen peroxide 45 g/L for 60 min and spores of vaccine strain of Bacillus anthracis exposed for 30 min were higher than 99.9%.The natural logarithm of survival rate of different bacterial spores showed linear regression with exposure time to hydrogen peroxide foam disinfectant.In the range of 10℃~40℃,the efficacy of hydrogen peroxide foam disinfectant in killing B.subtilis var.niger spores was enhanced with increasing temperature.The adjuvant in hydrogen peroxide foam disinfectant formula had synergetic effect on germicidal efficacy and the synergetic efficacy coefficient in killing B.subtilis var.niger spores was 4.13.The average killing rates of Candida albicans on cloth strip exposed to the foam disinfectant solution containing hydrogen peroxide 15 g/L for 1 min,Staphylococcus aureus on cloth strip exposed to the foam disinfectant solution containing hydoogen peroxide 4.5 g/L for 5 min and Escherichia coli on cloth strip exposed to the foam disinfectant solution containing hydrogen peroxide 2.25 g/L for 1 min were 99.9%.The nutrient broth as organic substance had significant influence on efficacy of the hydrogen peroxide foam disinfectant in killing F_2 coliphage.Change of organic interfering substance content had no significant influence on efficacy of the hydrogen peroxide foam disinfectant in killing B.subtilis var.niger spores.Conclusion: The germicidal regnlarity of the hydrogen peroxide foam disinfectant essentially conforms to the germicidal regularity of common chemical disinfectant.

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Available abstract

In order to observe the germicidal regularity of hydrogen peroxide foam disinfectant,carrier immersion quantitative germicidal test was used to carry out systematic study in laboratory.Results:The average killing rates of Bacillus subtilis var.niger spores on cloth strip exposed to the stock solution of the foam disinfectant containing hydrogen peroxide 45 g/L for 60 min and spores of vaccine strain of Bacillus anthracis exposed for 30 min were higher than 99.9%.The natural logarithm of survival rate of different bacterial spores showed linear regression with exposure time to hydrogen peroxide foam disinfectant.In the range of 10℃~40℃,the efficacy of hydrogen peroxide foam disinfectant in killing B.subtilis var.niger spores was enhanced with increasing temperature.The adjuvant in hydrogen peroxide foam disinfectant formula had synergetic effect on germicidal efficacy and the synergetic efficacy coefficient in killing B.subtilis var.niger spores was 4.13.The average killing rates of Candida albicans on cloth strip exposed to the foam disinfectant solution containing hydrogen peroxide 15 g/L for 1 min,Staphylococcus aureus on cloth strip exposed to the foam disinfectant solution containing hydoogen peroxide 4.5 g/L for 5 min and Escherichia coli on cloth strip exposed to the foam disinfectant solution containing hydrogen peroxide 2.25 g/L for 1 min were 99.9%.The nutrient broth as organic substance had significant influence on efficacy of the hydrogen peroxide foam disinfectant in killing F_2 coliphage.Change of organic interfering substance content had no significant influence on efficacy of the hydrogen peroxide foam disinfectant in killing B.subtilis var.niger spores.Conclusion: The germicidal regnlarity of the hydrogen peroxide foam disinfectant essentially conforms to the germicidal regularity of common chemical disinfectant.

Key concepts: Disinfectant, Hydrogen peroxide, Spore, Bacillus subtilis, Chemistry, Microbiology, Peroxide, Stock solution

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