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2012•The Journal of Medical Theory and PracticeRequires access

Clinical Observation of Creatine Phosphate Sodium on Treating Myocardial Damage due to Neonatal Asphyxia

Jiang Chi-qi

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Abstract

Objective:To observe the effect of creatine phosphate sodium injection on treating myocardial damage due to neonatal asphyxia.Methods:60 newborns with myocardial damage due to neonatal asphyxia were randomly divided into treatment group(n=32)and control group(n=28).Both two groups were treated with conventional treatment.On the basis of control group,treatment group was administrated with creatine phosphate sodium intravenously,0.5g,qd,and 7 days as a course.The changes of symptoms,physical signs,CK-MB and cTnI were observed during the treatment.Results:The total effective rate was 96.9% in the treatment group and 75% in the control group(P0.01).The improvement of CK-MB and cTnI in the treatment group were all superior to those in the control group(P0.01).Conclusion:CP has better effects on the hypoxic ischemic myocardial damage due to neonatal asphyxia.

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What this paper is about

Objective:To observe the effect of creatine phosphate sodium injection on treating myocardial damage due to neonatal asphyxia.Methods:60 newborns with myocardial damage due to neonatal asphyxia were randomly divided into treatment group(n=32)and control group(n=28).Both two groups were treated with conventional treatment.On the basis of control group,treatment group was administrated with creatine phosphate sodium intravenously,0.5g,qd,and 7 days as a course.The changes of symptoms,physical signs,CK-MB and cTnI were observed during the treatment.Results:The total effective rate was 96.9% in the treatment group and 75% in the control group(P0.01).The improvement of CK-MB and cTnI in the treatment group were all superior to those in the control group(P0.01).Conclusion:CP has better effects on the hypoxic ischemic myocardial damage due to neonatal asphyxia.

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Available abstract

Objective:To observe the effect of creatine phosphate sodium injection on treating myocardial damage due to neonatal asphyxia.Methods:60 newborns with myocardial damage due to neonatal asphyxia were randomly divided into treatment group(n=32)and control group(n=28).Both two groups were treated with conventional treatment.On the basis of control group,treatment group was administrated with creatine phosphate sodium intravenously,0.5g,qd,and 7 days as a course.The changes of symptoms,physical signs,CK-MB and cTnI were observed during the treatment.Results:The total effective rate was 96.9% in the treatment group and 75% in the control group(P0.01).The improvement of CK-MB and cTnI in the treatment group were all superior to those in the control group(P0.01).Conclusion:CP has better effects on the hypoxic ischemic myocardial damage due to neonatal asphyxia.

Key concepts: Medicine, Asphyxia, Creatine, Anesthesia, Phosphate, Troponin I, Sodium, Internal medicine

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