Optimization of the Decocting Technolgoy of Solid Preparation of Sansheng Decoction by Orthogonal Experiment Method

Objective:To screen and optimize the decoction process for providing the basis of the solid preparation of Sansheng Decoction.Method:The extract yield and the contents of Pinoresinol Diglucoside and Chlorogenic acid were used as marks to select the best conditions of the solid preparation of Sansheng Decoction through single factor and orthogonal experiment method.Results:The best producing conditions are as follows:the boiling temperature is 140℃,the decoction time is 20min and the solid-liquid ratio is 1∶ 22.5.Conclusion:The solid decoction by the above method is stable,the operation is feasible and more simple,convenient,time-saving comparing with the traditional decoction.