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2014•Liaoning Zhongyiyao Daxue xuebaoRequires access

Research and Analysis on Fingerprint in Rupikang Capsules

Jun‐Xian Wang

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Abstract

Objective:To research and analyze the fingerprint in Rupikang Capsules.Methods:HPLC analysis was carried out on Agilent ZORBAX SB-C18(4.6 mm×250 mm,5μm).Water-0.1% phosphoric acid water-acetonitrile mixture was as mobile phase,linear gradient elution;sample quantity:20μL;column temperature:30 ℃;detection wavelength at 280 nm.Traditional Chinese medicine(TCM)chromatographic fingerprint similarity evaluation system(version 2004A)was used.Results:Common peak is separated well.Conclusion:This method provides more comprehensive information about quality standard of Rupikang Capsules and is good to control the quality of the production.

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What this paper is about

Objective:To research and analyze the fingerprint in Rupikang Capsules.Methods:HPLC analysis was carried out on Agilent ZORBAX SB-C18(4.6 mm×250 mm,5μm).Water-0.1% phosphoric acid water-acetonitrile mixture was as mobile phase,linear gradient elution;sample quantity:20μL;column temperature:30 ℃;detection wavelength at 280 nm.Traditional Chinese medicine(TCM)chromatographic fingerprint similarity evaluation system(version 2004A)was used.Results:Common peak is separated well.Conclusion:This method provides more comprehensive information about quality standard of Rupikang Capsules and is good to control the quality of the production.

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Available abstract

Objective:To research and analyze the fingerprint in Rupikang Capsules.Methods:HPLC analysis was carried out on Agilent ZORBAX SB-C18(4.6 mm×250 mm,5μm).Water-0.1% phosphoric acid water-acetonitrile mixture was as mobile phase,linear gradient elution;sample quantity:20μL;column temperature:30 ℃;detection wavelength at 280 nm.Traditional Chinese medicine(TCM)chromatographic fingerprint similarity evaluation system(version 2004A)was used.Results:Common peak is separated well.Conclusion:This method provides more comprehensive information about quality standard of Rupikang Capsules and is good to control the quality of the production.

Key concepts: Gradient elution, Medicine, Phosphoric acid, Fingerprint (computing), Chromatography, High-performance liquid chromatography, Similarity (geometry), Biomedical engineering

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