The Clinical Relationship Analysis between Obstructive Sleep Apnea Syndrome(OSAHS) and Hypertension

Objective: To research the clinical relationship and mechanism between obstructive sleep apnea syndrome(OSAHS) and hypertension.Method: 258 patients were allocated to pure treating sleep apnea(N) and Pure OSAHS(O) and OSAHS and hypertension(O+H) according to patient's intention and condition.Three groups of patients with clinical foundation data collection,ESS questionnaire survey and EP score,polysomnography monitoring and blood pressure measurement.Results: The difference of which all three groups on age,sex,smoking,drinking was no significant difference(P0.05).But compared with control group,OSAHS group and OSAHS + HT group,the difference of BMI and NC was statistically significant(P0.05);The difference of which OSAHS group and OSAHS + HT group compared with the control group on AHI,Ts90,LsaO2,MsaO2 is statistically significant(P0.05);The difference of which OSAHS group and OSAHS + HT group compared with control group on systolic and diastolic blood pressure before and after sleeping,is statistically significant(P0.05).Conclusion: We concluded that OSAHS is associated with hypertension closely,chronic intermittent hypoxia is the cardinal mechanism which causing hypertension.