Effect of Maivelow on poor responders undergoing in vitro fertilization-embryo transfer cycles

Objective To study the effects of Maivelow administered before the stimulation cycle on poor responder patients undergoing in vitro fertilization-embryo transfer(IVF-ET) cycles.Methods 52 poor responder patients undergoing IVF-ET cycles were divided into 2 groups according to the history whether the patients had been treated with Maivelow before the ovulatory period(research group,n=24) or not treated with the drug(control group,n=28).A statistical analysis of the anamnestic data of the patients was carried out for the assessment of the ovulation-promoting effect of Maivelow and their influence on the IVF-ET operation.ResultsThe required dosis of gonadotrophin was lower in patients pre-treated with Maivelow than that in patients of the control group.The fertilization rate and number of good embryo more than the control group(P0.05).The differences between patients of the two groups with respect to number of oocyte retrieval,the cycle cancel rate and clinical pregnancy rate were not significant.Conclusion Maivelow administered before IVF-ET can improve the effects of ovulation-promotive treatment,increase the fertilization rate and number of good embryo in poor responder patients.