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2006•Zhongguo linchuang yixueRequires access

The Relationship between Insulin Resistance and Coronary Artery Disease

Qi Feng

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Abstract

Objective: To investigate the relationship between insulin resistence and the severity of coronary heart disease (CHD). Methods:238 patients with CHD who undergone coronary angiography were included in this study . According to the angiography results,patients were divided into CHD group (n=153) and control group (n=85). The severity of coronary artery lesions and levels of plasma lipids,plasma glucose, insulin and body mass index(BMS) were measured. Results: Compared to the control group,IR,TC,TG,and LDL levels in CHD group increased significantly. There were correlationship between insulin resistance index(IRI) and the classification of coronary artery lesions,P0.001.Conclusion:Higher IRI has positive relation with the severity of coronary artery lesions. Improving insulin sensitivity would decrease cardiovascular risk in high risk population.

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What this paper is about

Objective: To investigate the relationship between insulin resistence and the severity of coronary heart disease (CHD). Methods:238 patients with CHD who undergone coronary angiography were included in this study . According to the angiography results,patients were divided into CHD group (n=153) and control group (n=85). The severity of coronary artery lesions and levels of plasma lipids,plasma glucose, insulin and body mass index(BMS) were measured. Results: Compared to the control group,IR,TC,TG,and LDL levels in CHD group increased significantly. There were correlationship between insulin resistance index(IRI) and the classification of coronary artery lesions,P0.001.Conclusion:Higher IRI has positive relation with the severity of coronary artery lesions. Improving insulin sensitivity would decrease cardiovascular risk in high risk population.

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Available abstract

Objective: To investigate the relationship between insulin resistence and the severity of coronary heart disease (CHD). Methods:238 patients with CHD who undergone coronary angiography were included in this study . According to the angiography results,patients were divided into CHD group (n=153) and control group (n=85). The severity of coronary artery lesions and levels of plasma lipids,plasma glucose, insulin and body mass index(BMS) were measured. Results: Compared to the control group,IR,TC,TG,and LDL levels in CHD group increased significantly. There were correlationship between insulin resistance index(IRI) and the classification of coronary artery lesions,P0.001.Conclusion:Higher IRI has positive relation with the severity of coronary artery lesions. Improving insulin sensitivity would decrease cardiovascular risk in high risk population.

Key concepts: Medicine, Internal medicine, Insulin resistance, Cardiology, Body mass index, Coronary artery disease, Coronary angiography, Artery

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