2006•Zhongguo jiceng yiyaoRequires access
The relationship between expression of VEGF in colorectal cancer and pathological factors
L Chen
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Abstract
Objective To explore the correlation between expression of VEGF in colorectal cancer and pathological factors.Methods The expression of VEGF in 99 cases with colorectal cancer was examined by immunohistochemical staining.Results It showed that the expression of VEGF in colorectal cancer was correlated with depth of invasion and lymph node metastasis and was not correlated with tumor region,and histologic type.The frequency of positive cases in patients with lymph node metastasis was significantly higher than that in patients without lymph node metastasis(P0.05).Conclusion VEGF might be a recurrence and prognostic indicator in patients with colorectal cancer.It is very useful for patients with colorectal cancer in higher expression of VEGF adopting adjuvant chemotherapy and radiotherapy.