Diagnostic value of combination detection of 4 tumor markers on breast cancer

Objective To investigate the value of serum CA153,CA125,CA199 and CEA combined detection on early diagnosis of breast cancer.Methods Serum CA153,CA125,CA199 and CEA levels in the patients with benign breast diseases and breast cancer were detected by chemiluminescence.Results The sensitivity of the combined detection of 4 tumor markers CA153,CA125,CA199 and CEA in breast cancer was obviously higher than that of the single detection(all P0.01).Conclusion The positive rate and sensitivity of the combined detection of serum markers CA153,CA125,CA199 and CEA in the patients with breast cancer will be increased by a large margin.Although the combined detection of 4 tumor markers is not as the specific indicator of breasr cancer,but it could provide more important basis for its early detection and diagnosis in clinic.