Curative Observation of Shenfu Injection on Treating Chronic Heart Failure in Elderly Patients with Pulmonary Heart Disease

We aimed to assess the clinical efficiency of Shenfu Injection on chronic heart failure of elderly patients(≥ 60years) with pulmonary heart disease.Methods: 108 elderly patients with chronic heart failure of pulmonary heart disease were enrolled.54 patients were randomly allocated to receive Shenfu Injection and routine therapy(Shenfu group) and 54 were allocated to receive only routine treatment(controlled group) such as oxygen,anti-infection,diuretic,cardiotonic,vasodilator and other therapeutic measures.The effect of treatment for chronic heart failure between the two groups was compared.In addition,the precursor of plasma amino-terminal pro-B-type natriuretic peptide(NT-proBNP),blood gas analysis were assessed during the study period.Results: Individuals in the Shenfu group had a greater improvement in heart function than those in controlled group(88.9% vs 77.2%,P0.05).The serum level of NT-proBNP was significantly lower in the Shenfu group(P0.05).Furthermore,the blood gas analysis in Shenfu group compared with the controlled group was significantly improved(P0.01).Conclusion: The combination of Shenfu Injection and routine treatment in elderly patients with chronic heart failure of pulmonary heart disease can improve the therapeutic effect.