Analysis of chromosome karyotypes of 108 dysplastic patient

Objective: To analyze the relationship between abnormal karyotypes and abnormal fertility.Methods: To research peripheral blood lymphocytes of 108 dysplastic patients who is younger than 18,and the abnormal karyotype were analyzed.Results: There were 26 cases of abnormal karyotypes in 108 patients with genetic counseling and the abnormal rate is 24.1%.In chromosomal abnormal karyotypes,there were 9 cases of sex chromosome abnormalities,accounting for 8.3%;and there were 17 cases of euchromosome abnormalities,accounting for 15.7%.And there were 82 cases of dysplasia who had normal chromosome karyotypes,accounting for 75.9%.Conclutions: Abnormal karyotype is closely related to dysplasia,karyotype analysis is conducive to clinical diagnosis,but also provide the basis for genetic counseling.