Clinical Study on Treatment for Advanced Non-small-cell Lung Cancer by ZhenQi YiQi Capsule Combined with GP Regimen

Objective: To observe short-term effects and toxicity of ZhenQi YiQi capsule combined with GP regimen(gemcitabine and cis-platinum complexes) in treating advanced non-small-cell lung cancer, and its effects on progression-free survival. Methods: Sixty-seven patients were randomized into 34 cases of the treatment group and 33 cases of the control group. The treatment group were given with ZhenQi YiQi capsule combined with GP regimen, and the control group GP regimen. 21 days were one course of the treatment, curative effects were observed after treating for four courses of the treatment. Results: Effective rate and disease control rate of the treatment group were 47.1% and 79.41% respectively, higher than 39.4% and 63.63% of the control group, but the comparison had no statistical meaning(P0.05); life quality and symptom improvements of the patients in the treatment group were superior to these of the control group, the difference presented statistical meaning(P0.05); the treatment group was obviously lower than the control group in the cases with leucopenia, nausea and vorniting(P0.05); the difference had statistical meaning in the comparison of progression-free survival between both groups(P0.05).Conclusion: ZhenQi YiQi capsule combined with GP regimen could improve the symptoms of the patients with advanced non-small-cell lung cancer, relieve the toxicity of chemotherapy, raise life quality of the patients and prolong progression-free survival of the patients.