Preparation and Characterization of Magnetic Chitosan Microspheres for the Carriers of Radionuclides in Therapy

In this paper, magnetic chitosan microspheres which can load radionuclides were prepared by the suspension cross-linking technique. The results demonstrated that the concentration of chitosan solution, Fe 3O 4/chitosan ratio and stirring rate of the suspension medium were the most effective parameters for the size/size distribution, morphology and magnetism of magnetic chitosan microspheres. Furtherly, the best preparation circuit is optimized. Finally, the size, size distribution, morphology and magnetism were studied by different instruments.