Preparation and characteristics of magnetic chitosan microspheres

The Fe3O4 nanoparticles were prepared by co-precipitation and modified by oleic acid and the composite chitosan magnetic microspheres containing Fe3O4 nanoparticles were prepared using the emulsification cross-linking technique by adding proper amount of glutaraldehyde into chitosan solution.The results demonstrated that the chitosan concentration,NaOH amount and stirring speed of the suspension medium were the most effective parameters for the size,size distribution,morphology and magnetism of magnetic chitosan microspheres.The SEM,IR and DLS indicated that the diameter of the microspheres was about 348.5 nm and the microspheres were uniformly disperse.The magnetic test showed that the microspheres had good magnetic responsiveness and the functional groups on the surface.