Treatment of chronic severe hepatitis B by Jieduan Niwan method

Objective:To evaluate initially therapeutic effect of the Jieduan Niwan method on chronic severe hepatitis B.Methods:About 110 patients were selected and received the treatment of TCM and western medicine or the treatment of only western medicine,to evaluate initially the effect by the comparison of effective rate,frequency of complication,case fatality rate and the main laboratory indexes.Results:First The effect on syndrome:After eight weeks'treatment,the effective rate (40cases,72.73%) in the treatment group was higher than in the control group (30 cases,53.57%),and the difference between them was significant (P0.05).Second The effect on liver function:①Total bilirubin (TBil):After two weeks' treatment TBil of the two groups decreased remarkably.And the difference in the treatment group was all significant compared TBil before treatment with after two weeks'treatment (P0.05),four week's treatment (P0.01) and eight weeks'treatment (P 0.05).②Blood cloting function:in the treatment group PTA was significant increased after treatment.And the difference between on week's therapy (43.6%) and pretherapy (35.0%) was significant (P0.01).But there was no significant difference in the control group.After one week's treatment PTA in the treatment group (43.6%) was higher remarkably than in the control group (33.4%),and the difference was remarkably significant (P0.01).Third The compositive effect:The effective rate (37 cases,67.27%) in the treatment group was higher than in the control group (30 cases,53.57%),and the difference between them was not significant (P0.05).The case fatality rate (5 cases,9.09%) in the treatment group was lower than in the control group (13 cases,23.21%),and the difference between them was significant (P0.05).Conclusion:The effect in the treatment group was better than in the control group,especially in recoverying syndrome,liver function (such as TBil,blood cloting function) etc.Which proved the rationality of the principle.