Observing the Effect of Enalapril Betaloc Spironolactone on Chronic Heart Failure

Objective: To explore the efficacy of enalapril,betaloc,spironolactone on chronic heart failure.Method: 326 cases of patients with chronic heart failure from 2008 January to 2013 June in the First People's Hospital of Chongqing new North Zone were analyzed retrospectively,and 168 cases in the treatment group,combined with betaloc,enalapril spironolactone,based on conventional anti heart failure treatment.158 cases in the control group only received conventional anti heart failure treatment,the two groups were compared before and after treatment.Result: The clinical curative effect in treatment group were 88 cases(52.3%),effective in 68 cases( 40.4%),invalid 12 cases( 7.3%),the total efficiency was 92.7%.The control group were 40 cases( 25.2%),effective in 56 cases( 36.2%),invalid 62 cases( 38.6%),the total efficiency was 61.4%.The total efficiency of two groups had significant difference( P 0.05).Comparison of doppler echocardiography: measurement of cardiac function and left ventricular diameter for a period of 3months after the treatment in the two groups,the treatment group of left ventricular end diastolic diameter( LVEDD),left ventricular end systolic diameter( LVESD) were decreased,left ventricular ejection fraction( LVEF) were increased,patients in the treatment group were compared before and after treatment with different statistical significance( P 0.05).The treatment group compared with the control group had significant difference( P 0.05).The control group before and after treatment the index did not change significantly,the difference was not statistically significant( P 0.05).Conclusion: Betaloc,enalapril,spironolactone in the treatment of chronic heart failure can improve the patients with heart failure symptoms,changes the left ventricular remodeling,improve left ventricular ejection fraction,improve the effective rate of patients with heart failure,reduce the rate of hospitalization.