ScholarLens Back to search
2013•Chinese Journal of Health Laboratory TechnologyRequires access

The diagnostic value of N-acetyl-β-D-glocosaminidase,Kidney injury molecule and neutrophil gelatinase-associated lipocalin in patients with acute kidney injury

Yang Zhi-don

Open publisher page 0 citations

Abstract

Objective:To investigate the clinical value of N-acetyl-β-D-glocosaminidase(NAG),kidney injury molecule 1(KIM-1) and neutrophil gelatinase-associated lipocalin(NGAL) in patients with acute kidney injury(AKI).Methods:Seventy-two AKI patients(AKI 1,AKI 2 and AKI 3) and 50 healthy people were involved to detect the NAG,KIM-1 and NGAL in urine,GFR and Scr in plasma.Results:The GFR of the AKI group was significantly lower than control group(P 0.05),while the plasma Scr level of the AKI group was significantly higher than control group(P 0.05).The NAG,KIM-1 and NGAL in urine were positively correlated with plasma Scr level(P 0.05),but negatively correlated with GFR(P 0.05).Conclusion:The NAG,KIM-1 and NGAL in urine of AKI is significantly correlated with kidney damage,it could be used a reliable index for judgment of AKI.

About this research paper

What this paper is about

Objective:To investigate the clinical value of N-acetyl-β-D-glocosaminidase(NAG),kidney injury molecule 1(KIM-1) and neutrophil gelatinase-associated lipocalin(NGAL) in patients with acute kidney injury(AKI).Methods:Seventy-two AKI patients(AKI 1,AKI 2 and AKI 3) and 50 healthy people were involved to detect the NAG,KIM-1 and NGAL in urine,GFR and Scr in plasma.Results:The GFR of the AKI group was significantly lower than control group(P 0.05),while the plasma Scr level of the AKI group was significantly higher than control group(P 0.05).The NAG,KIM-1 and NGAL in urine were positively correlated with plasma Scr level(P 0.05),but negatively correlated with GFR(P 0.05).Conclusion:The NAG,KIM-1 and NGAL in urine of AKI is significantly correlated with kidney damage,it could be used a reliable index for judgment of AKI.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:To investigate the clinical value of N-acetyl-β-D-glocosaminidase(NAG),kidney injury molecule 1(KIM-1) and neutrophil gelatinase-associated lipocalin(NGAL) in patients with acute kidney injury(AKI).Methods:Seventy-two AKI patients(AKI 1,AKI 2 and AKI 3) and 50 healthy people were involved to detect the NAG,KIM-1 and NGAL in urine,GFR and Scr in plasma.Results:The GFR of the AKI group was significantly lower than control group(P 0.05),while the plasma Scr level of the AKI group was significantly higher than control group(P 0.05).The NAG,KIM-1 and NGAL in urine were positively correlated with plasma Scr level(P 0.05),but negatively correlated with GFR(P 0.05).Conclusion:The NAG,KIM-1 and NGAL in urine of AKI is significantly correlated with kidney damage,it could be used a reliable index for judgment of AKI.

Key concepts: Acute kidney injury, Lipocalin, Neutrophil gelatinase-associated lipocalin, Medicine, Internal medicine, Gastroenterology, Urine, Kidney

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
The diagnostic value of N-acetyl-β-D-glocosaminidase,Kidney injury molecule and neutrophil gelatinase-associated lipocalin in patients with acute kidney injury — Research Paper | ScholarLens