Rosuvastatin treatment of patients with acute cerebral infarction mechanism

Objective To investigate the rosuvastatin in patients with acute cerebral infarction treatment effect and its mechanism.Methods Beijing aerospace general hospital 2011 March to December 2012 treated 110 patients with acute cerebral infarction were randomly divided into observation group and control group 55cases.The control group were treated with conventional therapy,including protecting brain cells,control blood sugar and blood pressure,platelet aggregation;The observation control group patients on the basis of given rosuvastatin treatment.Continuous treatment for 12weeks as a course of treatment.Recorded before and after treatment were compared lipid,serum high sensitivity C-reactive protein(hs-CRP)levels,and patients with neurological deficit scores,evaluated. Results After treatment:control group of patients with lipid levels did not change significantly,but the observation group were significantly decreased,compared with the control group,the difference was statistically significant(P 0.05),two groups hs-CRP were decreased(P0.05),and the content of the observation group were lower than the control group(P0.05),two groups of patients were decreased neurological function,and the observation group was better than the control group(P0.05),total effective observation group higher(P0.05).Conclusion Rosuvastatin treatment of acute cerebral infarction patients,results worthy of recognition,which may be related to blood lipid lowering therapy and anti-inflammatory response mechanisms.