Clinical Significance of Serum Bilirubin and Blood-Lipid Level in Patients with Cerebral Infarction

Objective To explore the change of serum bilirubin and blood-lipid level in patients with cerebral infarction. Methods Serum total bilirubin,direct bilirubin,indirect bilirubin, total cholesterol, tri-glycerides, serum high-density lipoprotein cholesterol, serum low-density lipoprotein cholesterol, lipoprotein-a, apolipoprotein A1, apolipoprotein B was measured in 64 patients with cerebral infarction (the observed group) and 32 healthy controls. Apply SPSS 10.0 for windows to deal with all data, T test was used to compare between the groups. Results Serum bilirubin in patients in the observed group total bilirubin 16.464±7.442μmol/L,direct bilirubin 3.264±1.719μmol/L,indirect bilirubin 13.201±6.130μmol/L was higher than the patients in the control group. P0.01(TBIL) , P0.05 (IBIL);the level of indirect bilirubin was in positive correlation with the concentration of low-density lipoprotein cholesterol(r =0.213 ,P0.05). Serum total cholesterol, triglycerides, serum high-density lipoprotein cholesterol, apolipoprotein B was significantly increased in patients in the observed group (P0.01), serum low-density lipoprotein cholesterol, apolipoprotein A1 in patients in the observed group was significantly decreased in the patients in the observed group(P0.01). Conclusion It suggested that there were pathophysiological relationships between cerebral infarction and serum levels of bilirubin and blood-lipid.