Metformin is Joint Female Alcohol Progesterone Insulin Resistance Polycystic Ovarian Syndrome Treatment of Infertility Caused by Clinical Observation

Objective:Discusses application metformin is joint female alcohol c progesterone(diane-35) treatment insulin resistance(IR) polycystic ovarian syndrome(PCOS) of the clinical curative effect of infertility.Methods: 124 cases of insulin resistance(IR) polycystic ovarian syndrome(PCOS) infertility patients were randomly divided into two groups(the treatment group and the observation group),A group of menstrual 5 days or palace progestin retreat hemorrhages 5 days start,the direct application Clomiphene(CC)/Menotrophin(HMG)/chorionic gonadotropin(HCG) promote ovulation treatment 3 cycles,three and A half hours after the group B give metformin 500 mg,three times per day,and at the same time period since the second day is to give female alcohol c progesterone 1 piece/late,21 days,of three cycles,and then use A group of promoting ovulation treatment 3 cycle.Observe both groups of patients before and after treatment body mass index(BIM),fasting blood sugar(FGP),fasting insulin levels(FINS),luteinizing hormone(LH),erythropoietin follicle-stimulating hormone(FSH),estradiol(E2),testoster-one(T),prolactin(PRL),and will promote ovulation 2 groups after ovulation rate,pregnancy rate and abortion rate compared.Results:The treatment group in oral metformin is joint female alcohol c progesterone after 3 months,FGP,FINS,BIM,FSH and LH,T,LH/FSH than that of before treatment significantly(P0.05),and more the observation group of ovulation rate,the pregnancy rate increases,the abortion rate to decrease.Conclusion: In insulin resistance to sexual polycystic ovarian syndrome to promote ovulation before treatment of infertility,application metformin is joint female alcohol c progesterone can effectively reduce the androgen,improve insulin resistance,increase pregnancy rate,reduce the abortion rate.