Effect of Preemptive Analgesia with Flurbiprofen Axetil Injection in Eye Surgery

Objective To investigate the efficacy and safety of preemptive analgesia with Flurbiprofen axetil in eye surgery.Methods 90 patients undergoing eye surgery were randomly divided into 3 groups.The patients in group F received Flurbiprofen axetil injection 1 mg/kg 15 minutes before operation;the patients in group P received pethidine 1.0 to 2.0 mg/kg 15 minites before operation;and the patients in group N received saline as a control.The VAS,RSS,vital signs and adverse reactions were observed.Results The F group showed lower VAS at any time point than the P and N group.The RSS in the F group were less than that in the P group,The side effects in group F were also less than those in group P.Conclusion Flurbiprofen axetil can offer more effective and safer preemptive analgesia for perioperative pain relief in eye surgery without any obvious adverse reaction.