The Serum TNF-α and IL-6 Level Changes and its Clinical Significance in the Elderly Patients with Acute Cerebral Infarction

Objective: To observe the serum TNF-α and IL-6 level changes and discuss its clinical significance in the elderly patients with acute cerebral infarction.Methods: Collect 53 elderly patients with acute cerebral infarction,observe the serum TNF-α and IL-6 level changes the 7th day,the 9th day and the 11th day after admission and compare with 26 healthy people;analysis the correlation analysis of serum TNF-α and IL-6 levels with disease severity.Results: The elderly patients' TNF-α and IL-6 level were statistical higher than the healthy people's(P0.01);the serum TNF-α and IL-6 levels significantly decreased(P 0.05) with the progress of treatment;the aerum TNF-α and IL-6 levels were positively correlated(P 0.05) with the disease severity,the aerum TNF-α and IL-6 levels' reduction were positively correlated(P 0.05) with the disease severity after 11days' treatment.Conclusion: In the course of treating elderly patients with ACI,we should dynamic monitor the serum TNF-α and IL-6 levels,it could prompt the development of the lesions and guide the clinical treatment.