Relationship Between Morning Blood Pressure Surge and Cardiovascular Disease Risk Factor in Patients With Primary Hypertension

Objective:To explore the relationship between morning blood pressure surge(MBPS)and cardiovascular disease risk factor in patients with primary hypertension. Methods:A total of 322 patients were enrolled in this study.They were divided into two groups according to 24 h ambulatory blood pressure monitoring.MBPS group,n=149,and Non-MBPSgroup,n=173.Blood pressure at different time of the day,fasting blood glucose(FBG)and lipids were examined and compared between two groups. Results: The patients' age and FBG were significantly higher in MBPS group than those in Non-MBPS group,P0.01 respectively.The 24 h mean systolic blood pressure(24 hSBP),day mean SBP(dSBP),night mean SBP(nSBP),the 24 h mean pause pressure(24 hPP),dPP,nPP,24 h mean blood pressure(24 h MAP),dMAP,nMAP were all higher in MBPS group than those in Non-MBPS group,P0.05 respectively.Pearson relation and multiple regression analysis indicated that MBPS positively correlated with the age,24 hSBP and FBG,(β=0.301,0.240,0.250,P0.01 respectively). Conclusion: The 24hSBP,age and FBG are main influencing risk factors for MBPS.