Relationship between morning blood pressure surge and cardiovascular risk factor in primary hypertensive patients

Objective To investigate the relationship between morning blood pressure surge and cardiovascular risk factors in primary hypertensive patients. Methods According to the results of 24 h ambulatory blood pressure monitoring, 322 patients were classified as the morning BP surge group (MBPS group, n=149) and non-surge group (NMBPS group, n=173). Blood lipid and fasting blood glucose were recorded. Results Age, FBG, 24 h SBP, nSBP, dSBP, 24 h PP, dPP, nPP, 24 h MAP, dMAP, nMAP were higher in MBPS group than those in NMBPS group (p<0.01 or p<0.05). Pearson relation analysis showed that morning blood pressure level positively correlated with age (r=0.446, p<0.001), 24 h SBP (r=0.347, p<0.001), FBG (r=0.388, p<0.001), nSBP (r=0.166, p=0.043), dSBP (r=0.190, p=0.02), LDL C (r=0.244, p<0.01), TC (r=0.188, p=0.022); after adjusting other risk factors, multiple regression analysis showed age, 24 h SBP and FBG remained as predisposing risk factors for MBPS level. Conclusion Age, 24 h SBP and FBG are the important influencing factors of morning blood pressure surge.