Clinical Observation of Therapeutic Effects of Baibeining on Rotavirus Enteritis

Objective To investigate the therapeutic effects of Baibeining on rotavirus enteritis.Methods 76 cases of rotavirus enteritis were observed,which were randomly divided into treatment group(40 cases)and control group(36 cases).Patients in both treatment group and control group were basically treated with ribavirin(10 mg/(kg.d),iv),smectite powder and bifidobacterium(p.o.),and fluid infusion supportive treatment.Based on the basic intervention,Baibeining(100 g,tid,3～5 d)was applied in the treatment group,while interferon α1-b(1 mg/kg,qd,3～5 d)was applied in the control group.Results Obvious effective rate of treatment group was 70.0%,and total effective rate was 92.5%.Obvious effective rate of control group was 38.9%,and total effective rate was 72.2%.The difference between treatment group and control group was statistically significant(P0.05).The time for dehydration correction and hospitalization in treatment group were shorter than control group.The difference between treatment group and control group was statistically significant(P0.01).Conclusions Baibeining can effectively improve symptoms and physical signs in patients with rotavirus enteritis,and reduce the incidence of persisting diarrhea.The therapeutic effects of Baibeining are better than that of interferon.Furthermore,Baibeining has good taste and less adverse reactions