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2009•The Journal of Medical Theory and PracticeRequires access

The Clinical Observation of Curative Effect of Carvedilol for Chronic Congestive Heart Failure

Ruilian Chen

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Abstract

Objective:To investigate the curative effect and safety of carvedilol treatment on chronic congestive heart failure(CHF).Methods:71 cases with CHF were randomly divided into two groups:the carvedilol treatment group(treated group) and the conventional treatment group(control group),comparing changes of the left ventricular end-diastolic diameter(LVEDD),left ventricular end-systolic diameter(LVESD),left ventricular ejection fraction(LVEF),heart rate,blood pressure,cardiac function in two groups between before and after six-months' treatment,in order to observe the curative effect and safety of carvedilol.Results:The LVEDD,LVESD,blood pressure and heart rate reduces,and LVEF,cardiac function classification raised significantly.And the difference compared to control group had significance(P0.05).Conclusion:The carvedilol improve the cardiac function,enhance the remodeling of left ventricular,and it is safe and effective.

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What this paper is about

Objective:To investigate the curative effect and safety of carvedilol treatment on chronic congestive heart failure(CHF).Methods:71 cases with CHF were randomly divided into two groups:the carvedilol treatment group(treated group) and the conventional treatment group(control group),comparing changes of the left ventricular end-diastolic diameter(LVEDD),left ventricular end-systolic diameter(LVESD),left ventricular ejection fraction(LVEF),heart rate,blood pressure,cardiac function in two groups between before and after six-months' treatment,in order to observe the curative effect and safety of carvedilol.Results:The LVEDD,LVESD,blood pressure and heart rate reduces,and LVEF,cardiac function classification raised significantly.And the difference compared to control group had significance(P0.05).Conclusion:The carvedilol improve the cardiac function,enhance the remodeling of left ventricular,and it is safe and effective.

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Available abstract

Objective:To investigate the curative effect and safety of carvedilol treatment on chronic congestive heart failure(CHF).Methods:71 cases with CHF were randomly divided into two groups:the carvedilol treatment group(treated group) and the conventional treatment group(control group),comparing changes of the left ventricular end-diastolic diameter(LVEDD),left ventricular end-systolic diameter(LVESD),left ventricular ejection fraction(LVEF),heart rate,blood pressure,cardiac function in two groups between before and after six-months' treatment,in order to observe the curative effect and safety of carvedilol.Results:The LVEDD,LVESD,blood pressure and heart rate reduces,and LVEF,cardiac function classification raised significantly.And the difference compared to control group had significance(P0.05).Conclusion:The carvedilol improve the cardiac function,enhance the remodeling of left ventricular,and it is safe and effective.

Key concepts: Carvedilol, Medicine, Ejection fraction, Cardiology, Heart failure, Internal medicine, Cardiac function curve, Blood pressure

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