Drug-induced Liver Injury:An Analysis of 371 Cases
Liu Weijun
Abstract
Liu Weijun
Abstract
OBJECTIVE: To conduct a statistical analysis on 371 drug-induced liver injury cases for references of clinical rational drug use and drug safety evaluation.METHODS: In this retrospective study,a total of 371 drug-induced liver injury cases were analyzed with regard to patients' sex and age,medication,manifestation of side effects,and prognosis.RESULTS: A total of 12 categories(57 kinds) of drugs were involved in the 371 drug-induced liver injury cases,leading the first three places were all anti-tuberculosis drugs.CONCLUSION: Great attention should be attached to drug-induced liver injury to prevent adverse drug reactions.
A significance statement is not available in the OpenAlex record.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
OBJECTIVE: To conduct a statistical analysis on 371 drug-induced liver injury cases for references of clinical rational drug use and drug safety evaluation.METHODS: In this retrospective study,a total of 371 drug-induced liver injury cases were analyzed with regard to patients' sex and age,medication,manifestation of side effects,and prognosis.RESULTS: A total of 12 categories(57 kinds) of drugs were involved in the 371 drug-induced liver injury cases,leading the first three places were all anti-tuberculosis drugs.CONCLUSION: Great attention should be attached to drug-induced liver injury to prevent adverse drug reactions.
Key concepts: Drug, Liver injury, Medicine, Adverse drug reaction, Drug reaction, Pharmacology, Statistical analysis, Retrospective cohort study