Clinical investigation of simultaneous transurethral resection for treatment of superficial bladder tumor complicated with benign prostatic hyperplasia

Objective To evaluate the safety and clinical effect of simultaneous transurethral resection of superficial bladder tumor(TURBT) and transurethral resection of prostate(TURP).Methods The clinical data of 67 patients with SBC and BPH were retrospectively studied.The patients in test group(n = 32) underwent TURBT and TURP at the same time while those in control group received TURBT only.All the patients accepted the irrigation of bladder by Hydroxycamptothecin(20 milligram one time) according to the course of treatment.There was no significant difference between two groups in age,tumor size,tumor stage and grade(P 0.05).Results All patients were successfully operated.The following-up period ranged from one to three years,the average time was one point eight years.The bladder cancer recurrence rate was 46.9% and 45.7% in the control group.The average recurrent time was 16 months in the test group and 13 months in the control group.There were no significant differences between the two groups neither in average recurrence rates nor recurrent time(P 0.05).There were no prostatic urethra implantation recurrence occurred in test group.Conclusion Simultaneous TURBT and TURP is a safe and effective alternative treatment for the patients of superficial bladder cancer complicated with benign prostatic hyperplasia,and it would not increase tumor implantation at the prostatic urethra.