Curative Effect of Ozagrel Sodium Combined with Edaravone in Treating Acute Cerebral Infarction Patients

Objective: To observe the clinical effects of Ozagrel sodium combined with Edaravone in treating acute cerebral in-farction.Methods: 160 patients(92 male and 68 female,mean age of 68years) with noncardioembolic cerebral infarction were randomly divided into two groups,Oz-Ed Group and Control Group,80 cases in each group.Patients in control group were administered only with ozagrel;while patients in Oz-Ed group were administered with ozagrel and edaravone.We evaluated the clinical efficacy of the combination of these drugs in patients,and analyzed the changes of Nerve function defect score from 0 d(before treatment initiation) to 14 d.Results: The effectual rate was 85.9%(67/78)in Oz-Ed group,and was 70.9%(56/79)in control group.There was significant difference between the two groups,x2=5.12,P=0.022.The nerve function recovered much(P0.05)in both groups after treated for 14 days,as compared with that before treatment.There were also statistically significant difference between the two groups after treatment(P0.05).Conclusion:Combination therapy with ozagrel and edaravone had a better effect on acute cerebral infarction than single ozagrel therapy.It is an effec-tive therapy for acute cerebral infarction.