Progress in the Studies of the Structure and Function of Mitochondria Permeability Transition Pore

Mitochondrial permeability transition pore,also called mitochondrial mega channel,is across the mitochondrial membrane between inside and outside the high conductivity of non-selective channel,multi-protein complex formed by the.Most of the theories that it is caused by the opening of mitochondrial permeability transition is the mitochondrial pathway leading to apoptosis in many critical one.Thesis of its structure,mechanism and its relationship with apoptosis were reviewed.