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2009•Chinese Journal of Birth Health & HeredityRequires access

Molecular characteristic of G-type and P-type group A rotavirus among children with diarrhea.

Jing Liu

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Abstract

Objective: To investigate the epidemiology and genotypes of Group A Rotavirus among children with diarrhea.Methods:From January to December 2008,1 560 stool specimens collected from children with diarrhea,were tested by enzyme-linked immunosorbant assay(ELISA) and reverse transcription nested polymerse chain reaction(RT-nPCR) to identify the rotavirus infection and the G/P genotypes respectively.Results: Enzyme-linked immunosorbant assay(ELISA) results showed that Rotavirus A was present in 19.8%(309 cases) of the 1560 specimens without gender priority.G genotype identified G3 at 49.8%,G1 24.6% and mixed-G 13.3%.P genotype identified P[8] at 55.3% and P[4] 23.3%.Conclusion: Rotavirus A was the significant pathological agent of children with diarrhea.G3 and P[8]were the most prevalant G/P genotypes.

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Objective: To investigate the epidemiology and genotypes of Group A Rotavirus among children with diarrhea.Methods:From January to December 2008,1 560 stool specimens collected from children with diarrhea,were tested by enzyme-linked immunosorbant assay(ELISA) and reverse transcription nested polymerse chain reaction(RT-nPCR) to identify the rotavirus infection and the G/P genotypes respectively.Results: Enzyme-linked immunosorbant assay(ELISA) results showed that Rotavirus A was present in 19.8%(309 cases) of the 1560 specimens without gender priority.G genotype identified G3 at 49.8%,G1 24.6% and mixed-G 13.3%.P genotype identified P[8] at 55.3% and P[4] 23.3%.Conclusion: Rotavirus A was the significant pathological agent of children with diarrhea.G3 and P[8]were the most prevalant G/P genotypes.

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Available abstract

Objective: To investigate the epidemiology and genotypes of Group A Rotavirus among children with diarrhea.Methods:From January to December 2008,1 560 stool specimens collected from children with diarrhea,were tested by enzyme-linked immunosorbant assay(ELISA) and reverse transcription nested polymerse chain reaction(RT-nPCR) to identify the rotavirus infection and the G/P genotypes respectively.Results: Enzyme-linked immunosorbant assay(ELISA) results showed that Rotavirus A was present in 19.8%(309 cases) of the 1560 specimens without gender priority.G genotype identified G3 at 49.8%,G1 24.6% and mixed-G 13.3%.P genotype identified P[8] at 55.3% and P[4] 23.3%.Conclusion: Rotavirus A was the significant pathological agent of children with diarrhea.G3 and P[8]were the most prevalant G/P genotypes.

Key concepts: Rotavirus, Diarrhea, Genotype, Virology, Group A, Medicine, Biology, Gastroenterology

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Molecular characteristic of G-type and P-type group A rotavirus among children with diarrhea. — Research Paper | ScholarLens